Cerebral Hemispheres 2
NEUROSCIENTIFICALLY CHALLENGED

NEUROSCIENCE MADE SIMPLER

Sensation and Perception Questions

1. The optic disc is a part of the eye where:

  • A. we have our highest density of photoreceptors
  • B. there are no photoreceptors present
  • C. there are only rods (but no cones) present
  • D. there are only cones (but no rods) present
Show Answer

Correct answer: B

The optic disc is a part of the retina where the axons of retinal ganglion cells leave the eye to form the optic nerve. The optic disc lacks photoreceptors, thus creating a small "blind spot" in our visual field. We do not typically notice the blind spot because the brain uses information from the other eye to make the visual scene appear intact. Go to this link for a quick demonstration of the existence of your blind spot:

2. Destiny accidentally touches a hot stove and experiences immediate pain. The pain is sent to her brain primarily along which of these pathways?

  • A. corticospinal tract
  • B. dorsal columns-medial lemniscus tract
  • C. spinothalamic tract
  • D. spinocerebellar tract
Show Answer

Correct answer: C

The spinothalamic tract, which is part of the larger anterolateral pathway in the spinal cord, is the main pathway for carrying pain and temperature information to the brain. See this article for more info:

3. What is the correct term for the small bumps that cover the tongue?

  • A. taste buds
  • B. papillae
  • C. taste receptors
  • D. microvilli
Show Answer

Correct answer: B

The small bumps that cover the tongue are sometimes mistakenly called taste buds, but the correct term for them is papillae. Taste buds are found in the walls of the papillae, with each papilla containing anywhere from a just a few to hundreds of taste buds. Each taste bud contains 50-150 taste receptor cells, which interact with the substances in the mouth through microvilli that extend into the mouth.

4. These cells are the main receptor cells for both the auditory and vestibular systems:

  • A. Bipolar cells
  • B. Purkinje cells
  • C. Hair cells
  • D. Basket cells
Show Answer

Correct answer: C

Hair cells get their name because they have small hair-like projections called stereocilia. The stereocilia deflect in response to mechanical forces, with the result being the production of electrochemical signals used to convey sensory information. Hair cells in the cochlea are responsible for creating signals to transmit information about sound waves, while those in the vestibular system are responsible for creating signals to transmit information about head movement.

5. If you are outside at night and moonlight is the only illumination, will rods or cones contribute more to your vision?

  • A. rods
  • B. cones
  • C. rods and cones would both contribute equally to vision in moonlight
Show Answer

Correct answer: A

Rods are sensitive to low levels of illumination, but cones do not function effectively at low light levels. In typical moonlight levels of illumination, rods would be the primary source of information for vision. Since rods don't allow for color perception, we typically see in grayscale in low levels of illumination. Often, we may believe we perceive color at these low light levels, but it is caused by our brain "applying" color based on the expected color due to previous experience.

6. True or False - Due to the high density of pain receptors in brain tissue, damage to brain tissue itself causes extreme pain.

  • A. True
  • B. False
Show Answer

Correct answer: B

Even though the brain is where we process (and become aware of) pain in the body, there are no pain receptors in brain tissue itself. This explains how brain surgery can be performed on awake patients---a procedure known as "awake craniotomy"---without them feeling pain from manipulation of their brain tissue. While brain tissue doesn't have pain receptors, however, there are structures in the cranium that are pain-sensitive, such as the meninges (particularly the dura mater).

7. Color blindness (aka color vision deficiency), is much more common in males (up to 8% of males) than females (up to .5% of females). What is the main reason for this?

  • A. males are more likely to engage in risky behavior (e.g., smoking, drinking)
  • B. most types of color blindness are linked to mutations on the X chromosome
  • C. females are culturally taught to recognize nuances in color from an early age
  • D. males have lower serotonin levels, and this is a risk factor for color blindness
Show Answer

Correct answer: B

The genetic mutations that commonly lead to color blindness are frequently found on the X chromosome. Because females have two X chromosomes, if there is a mutation on an X chromosome gene in a female, it is more likely to be balanced out by a "healthy" gene on the other X chromosome. In males, however, a mutation on an X chromosome gene is more likely to have an influence due to a lack of another X chromosome and thus a lack of a "healthy" gene to counteract the mutation.

8. You run your fingers across the top of your desk and perceive that it is solid but has a smooth surface. Which pathway below was most responsible for carrying this particular sensory information to your brain?

  • A. corticospinal tract
  • B. dorsal columns-medial lemniscus
  • C. spinothalamic tract
  • D. spinocerebellar tract
Show Answer

Correct answer: B

The dorsal columns-medial lemniscus pathway is the main pathway that carries tactile sensations---including sensations of touch, pressure, and vibration---to the brain. It also carries information about proprioception. Neurons in the dorsal columns travel up the spinal cord and synapse in the brainstem on neurons that form the second part of the pathway: the medial lemniscus. This travels up to the somatosensory cortex, which is the main cortical area for processing touch sensations.

9. These fluid-filled structures help our brain to perceive head movement, as when the head is moved the fluid in one of these structures also moves, causing the stimulation of receptors called hair cells:

  • A. Eustachian tubes
  • B. semicircular canals
  • C. lacrimal glands
  • D. cochleae
Show Answer

Correct answer: B

The semicircular canals consist of three tubes, positioned approximately at right angles to one another, that are each situated in a plane in which the head can rotate. This design allows each of the canals to detect one of the following head movements: nodding up and down, shaking side to side, or tilting left and right.

10. The optic nerve carries visual information from the eye to the optic chiasm, where it then mixes with fibers from the optic nerve from the opposite eye to form the:

  • A. optic tectum
  • B. lateral geniculate nucleus
  • C. optic radiations
  • D. optic tract
Show Answer

Correct answer: D

At the optic chiasm, about 60% of the axons from the optic nerve cross over to the other side of the brain, while the rest stay on the side they originated on. The result of this is that all of the information from the right visual field ends up traveling to the left side of the brain, and vice versa. After the optic chiasm, the visual fibers are no longer called the optic nerve; they’re now called the optic tract.

11. Almost all incoming sensory information is sent to the thalamus before it is sent to the cortex to be processed. Information from this sense is an exception; it bypasses the thalamus and goes directly to the cortex to be processed.

  • A. touch
  • B. smell
  • C. vision
  • D. taste
Show Answer

Correct answer: B

Olfaction, or smell, is unique in that olfactory information does not get sent to the thalamus before being sent to the cortex. Instead, it is sent to the olfactory cortex, where the initial processing of olfactory information occurs. It's unknown why exactly this unique pathway exists; some have hypothesized it is an evolutionary adaptation to enable faster processing of olfactory information.

12. This coiled structure was named for its resemblance to a snail's shell; it contains the main receptor organ for hearing:

  • A. tectum
  • B. cochlea
  • C. colliculus
  • D. trigone
Show Answer

Correct answer: B

The cochlea is a coiled structure that resembles a snail shell (cochlea comes from the Greek kochlos, which means "snail"); it is found within the inner ear. It contains the organ of Corti, which is the main receptor organ for hearing.

13. These receptors are responsible for detecting painful stimuli:

  • A. mechanoreceptors
  • B. proprioceptors
  • C. nociceptors
  • D. thermoreceptors
Show Answer

Correct answer: C

Nociceptors are cutaneous receptors that are specialized to detect noxious stimuli like extreme pressure, very hot or cold temperatures, or tissue damage. When activated, nociceptors convey information regarding a painful stimulus to the spinal cord, and from there it gets sent up to the brain.

14. Most of the neurons in the optic tracts terminate in this nucleus in the thalamus:

  • A. medial geniculate nucleus
  • B. lateral geniculate nucleus
  • C. ventral posterolateral nucleus
  • D. pulvinar nucleus
Show Answer

Correct answer: B

Most of the neurons in the optic tracts terminate in the lateral geniculate nucleus of the thalamus. Here, the optic tracts synapse on neurons that leave the lateral geniculate nucleus and extend toward the back of the brain as bundles of fibers called the optic radiations. The optic radiations travel back to the primary visual cortex.

15. Which cells carry visual signals out of the eye, forming the optic nerve?

  • A. photoreceptor cells
  • B. bipolar cells
  • C. ganglion cells
  • D. horizontal cells
Show Answer

Correct answer: C

The visual signal travels from photoreceptors to bipolar cells to ganglion cells. The ganglion cells carry the signal out of the eye, forming the optic nerve.

16. How does a cochlear implant improve hearing in someone who is deaf or has severe hearing loss?

  • A. it causes vibration of the eardrum to create the sensation of sound
  • B. it enhances auditory processing through stimulation of brainstem nuclei
  • C. it amplifies existing sound waves so they are loud enough to detect
  • D. it stimulates the auditory nerve to send auditory information to the brain
Show Answer

Correct answer: D

Cochlear implants involve a microphone that detects sound, as well as a sound processor that converts the sound into a radio frequency signal. The signal is transmitted to a receiver implanted under the skin behind the ear. The receiver decodes the signal, then converts it into electrical currents. The currents are sent along wires to stimulate the auditory nerve, which sends auditory information to the brain.

17. This part of the brain is best known for its role in pain inhibition. Neurons leave here and form part of a pathway that extends down to the spinal cord to inhibit the transmission of pain signals.

  • A. amygdala
  • B. hippocampus
  • C. precentral gyrus
  • D. periaqueductal gray
Show Answer

Correct answer: D

The periaqueductal gray, or PAG, is an area of gray matter found in the brainstem. Although the functions of the PAG are complex and not fully understood, it is best known for its role in the inhibition of pain.

18. Someone places an object in your hand while your eyes are closed. Even without opening your eyes, you are able to feel the object and tell that it is a key. What sensory pathway played the largest role in the perception required to determine what the object was?

  • A. spinothalamic tract
  • B. corticospinal tract
  • C. dorsal columns-medial lemniscus
  • D. spinoreticular tract
Show Answer

Correct answer: C

The dorsal columns-medial lemniscus pathway (also called the posterior columns-medial lemniscus) is the main pathway that carries tactile information to the brain. It carries information about fine touch, vibration, pressure, and proprioception (the sense of body position).

19. This area of the retina has a very high density of cones, and is responsible for our highest acuity vision:

  • A. optic disc
  • B. sclera
  • C. amacrine region
  • D. fovea
Show Answer

Correct answer: D

The fovea is a small, specialized area in the center of the retina. It's the area responsible for our sharpest, most detailed vision. The fovea contains mostly cone photoreceptors, which are responsible for color vision and fine detail. It has virtually no rods, which are more sensitive to low light but less precise.

20. Which of the following is a touch receptor?

  • A. bipolar cell
  • B. hair cell
  • C. olfactory receptor
  • D. Pacinian corpuscle
Show Answer

Correct answer: D

Pacinian corpuscles are rapidly-adapting touch receptors with very large receptive fields. They are thought to be most effective at transmitting information about vibrations objects cause when they are contacted or grasped by the hand. This information may be important for the use of tools.

21. When sound waves cause fluid to move within the cochlea, that fluid movement causes this structure to move as well, ultimately leading to the activation of hair cells and the perception of sound:

  • A. tympanic membrane
  • B. basilar membrane
  • C. ossicles
  • D. auditory nerve
Show Answer

Correct answer: B

The basilar membrane moves in response to fluid vibrations in the cochlea. This movement causes the hair cells' stereocilia to bend, which leads to their activation and the transmission of sound signals to the brain.

22. Conscious proprioception, or awareness of your body's position and movement, is mainly handled by which of the following pathways?

  • A. spinothalamic tract
  • B. corticospinal tract
  • C. reticulospinal tract
  • D. dorsal columns-medial lemniscus pathway
Show Answer

Correct answer: D

The dorsal columns-medial lemniscus pathway carries conscious proprioception (and fine touch, vibration, etc.) to your cerebral cortex for conscious awareness. Other pathways like spinocerebellar tracts handle unconscious proprioception, feeding it to the cerebellum for coordination (not conscious perception).

23. Where are olfactory receptors primarily located?

  • A. olfactory bulb
  • B. olfactory epithelium
  • C. olfactory cortex
  • D. nasal conchae
Show Answer

Correct answer: B

Olfactory receptors are located in the olfactory epithelium—a specialized area of tissue at the top of the nasal cavity. This is where odorant molecules first bind, initiating the sense of smell.

24. What change occurs in a rod photoreceptor when it is exposed to light, initiating the visual signal to the brain?

  • A. It becomes depolarized and releases more neurotransmitter
  • B. It becomes hyperpolarized and releases less neurotransmitter
  • C. It becomes hyperpolarized and releases more neurotransmitter
  • D. It becomes depolarized and releases less neurotransmitter
Show Answer

Correct answer: B

In darkness, rod photoreceptors are depolarized and continuously release the neurotransmitter glutamate. When exposed to light, a phototransduction cascade is triggered that leads to the closure of sodium channels, causing the cell to hyperpolarize. This hyperpolarization reduces glutamate release, which is the key signal that initiates changes in downstream retinal cells and ultimately leads to visual perception.

25. Which of the following structures/systems is most commonly affected in cases of vertigo?

  • A. olfactory cortex
  • B. vestibular system
  • C. motor cortex
  • D. auditory cortex
Show Answer

Correct answer: B

The vestibular system, which includes structures in the inner ear and their connections to the brain, plays a key role in balance and a sense of stability. Vertigo is typically associated with a disruption in function of either the vestibular system or one of the regions it communicates with to maintain our sense of balance.

26. Which of the following terms refers to the region where optic nerve fibers from both eyes partially cross and reorganize to form the optic tracts?

  • A. lateral geniculate nucleus
  • B. superior colliculus
  • C. visual cortex
  • D. optic chiasm
Show Answer

Correct answer: D

At the optic chiasm, fibers from the nasal (medial) half of each retina cross to the opposite side, while fibers from the temporal (lateral) halves stay on the same side. This partial crossing allows visual information from the same visual field to be processed together in the opposite hemisphere of the brain.

27. The sensory receptors (hair cells) of the semicircular canals are found in expansions of the semicircular canals called:

  • A. utricles
  • B. saccules
  • C. ampullae
  • D. cochlear ducts
Show Answer

Correct answer: C

The ampullae of the semicircular canals contain hair cells that respond to rotational movements of the head. The utricle and saccule detect linear acceleration, and the cochlear duct is involved in hearing.

28. Which of the following fibers carry information to the spinal cord about fast, sharp pain?

  • A. C fibers
  • B. A-beta fibers
  • C. A-delta fibers
  • D. D fibers
Show Answer

Correct answer: C

A-delta fibers are thinly myelinated and conduct signals relatively quickly, carrying information about fast, sharp, well-localized pain.

29. Which of the following cell types provides direct input to bipolar cells in the retina?

  • A. ganglion cells
  • B. optic nerve fibers
  • C. radial glia
  • D. photoreceptors
Show Answer

Correct answer: D

Photoreceptors (rods and cones) synapse directly onto bipolar cells, initiating the flow of visual information that will eventually reach the brain and form a visual scene.

30. A patient reports that lightly brushing their skin with clothing causes significant pain, even though the touch itself is not normally painful. This phenomenon is known as:

  • A. hypoesthesia
  • B. allodynia
  • C. analgesia
  • D. radiculopathy
Show Answer

Correct answer: B

Allodynia is pain triggered by a stimulus that does not normally cause pain, such as light touch, mild pressure, or gentle temperature changes. It often occurs in conditions where the nervous system becomes sensitized and misinterprets non-painful input as painful.


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