Periaqueductal gray - definition

area of grey matter in the midbrain that is involved in a descending pain control pathway. The periaqueductal gray, or PAG, receives pain information via the spinomescencephalic tract and then can activate the endogenous opiate system to suppress pain.

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2-Minute Neuroscience: Periaqueductal Gray

Know Your Brain: Periaqueductal Gray

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